P54 The combined anti-HIV-1 activity of emtricitabine and tenofovir with the integrase inhibitors elvitegravir or raltegravir show high levels of synergy in vitro (Poster not yet available)
R Kulkarni, R Hluhanich, D McColl, ME Abram, MD Miller and K White
Gilead Sciences, Inc., Foster City, CA, USA

P55 Phagocytic uptake of transmitted/founder virus-infected CD4 + T cells enhances macrophage infection
CJA Duncan, RA Russell, AE Baxter, AJ McMichael and QJ Sattentau
University of Oxford, Oxford, UK

P56 Discordant reconstitution of HIV-1- and CMV-specific responses in cART-treated HIV-1+ patients – what can we learn from co-infection?
N Grageda¹, SJ Westrop¹, A Jackson², S Mandalia², G Moyle², M Nelson² and N Imami^1
1Imperial College London, London, UK, ²Chelsea and Westminster Hospital, London, UK

P57 HIV-1 alters macrophage apoptosis in response to Streptococcus pneumoniae
P Collini, R Read and D Dockrell
University of Sheffield and Royal Hallamshire Hospital, Sheffield, UK

P58 Phenotypic characterisation of virus-specific T cells in treated HIV-1 infection: Profiling total and multimerspecific CD8 T cells
N Grageda¹, S Westrop¹, A Jackson², S Mandalia², G Moyle², M Nelson² and N Imami^1
1Imperial College London, London, UK, ²Chelsea and Westminster Hospital, London, UK

P59 How common is the mutation E138K in the UK? (Poster not yet available)
D Bradshaw¹, D Dolling², C Booth³, M Nelson¹, D Dunn² and D Asboe^1
1Chelsea and Westminster Hospital, London, UK, ²MRC Clinical Trials Unit, London, UK, ³Royal Free Hospital, London, UK

P60 Predictors of immunologic failure in treatment naive HIV infected patients who start highly active anti-retroviral therapy (HAART) (Poster not yet available)
A Tesema¹, A Kumie², A Showa-Amare³, A G-Yohannes¹ and T Gabrekidan^1
1Abt Associates Inc., Addis Ababa, Etthiopia, ²Addis Ababa University, Addis Ababa, Ethiopia, ³Zewditu Memorial Hospital, Addis Ababa, Ethiopia

P61 Cloning a defective SIVmac239 genome into modified vaccinia Ankara, MVA
G Cholapura-Puttaswamaiah¹ and T Blanchard^2
1University of Manchester, Manchester, UK, ²North Manchester General Hospital, Manchester, UK

P62 Comparison of CD4 response to cART in patients with HIV 1, HIV 2 and dual (HIV1/2) infected patients in a large ethnically diverse UK HIV cohort
S Shivasankar¹, L Campbell², S Adikari¹, M Sudhanva³ and C Taylor^1
1Department of HIV Medicine, King's College Hospital, London, UK, ²HIV Research Group, King's College London, London, UK, ³Department of Virology, King's College Hospital, London, UK

P63 Distinct HIV-1 Gag- and Nef- specific responses correlate with immunophenotype in treated chronic HIV-1 infection (Poster not yet available)
A Herasimtschuk¹, T Thaventhiran¹, M Nelson², G Moyle², B Gazzard², F Gotch¹ and N Imami^1
1Imperial College London, London, UK, ²Chelsea and Westminster Hospital, London, UK