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BHIVA/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) 2018


We aim to provide evidence-based guidance on best clinical practice in the provision, monitoring and support of pre-exposure prophylaxis (PrEP) for the prevention of HIV acquisition. The guidelines include:

(i) Guidance on risk assessment prior to PrEP;

(ii) Baseline assessment;

(iii) Dosing schedules;

(iv) Monitoring;

(v) Supporting adherence;

(vi) Buying generic PrEP; and

(vii) Cost-effectiveness.

The guidelines are aimed at clinical professionals directly involved in, and responsible for, HIV prevention, and at community advocates and organisations responsible for supporting HIV prevention strategies in those at risk of HIV acquisition.

A detailed review of the evidence base is included in Section 4. Sections 5 to 7 are intended to offer practical guidance in risk assessment, starting PrEP, ongoing management while on PrEP and stopping PrEP.


BHIVA/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP)NHS Evidence accredited provider

BHIVA BASHH PrEP guidelines

Additional information
BHIVA/BASHH PrEP guidelines proforma
PICO questions and search strategies

Consultation comments
Comments received by the BHIVA Secretariat during the public consultation process
Comments received from the BHIVA Executive Committee and Guidelines Subcommittee following revision after the web consultation

Declaration of interests
Declaration of interests from writing group members

Non-technical summary

These guidelines do not have a BHIVA non-technical summary, as many resources are already available. We suggest:

(NB These are links to external sites for which BHIVA has no responsibility)

Writing group

Michael Brady (Chair), Alison Rodger (Chair), David Asboe, Valentina Cambiano, Dan Clutterbuck, Monica Desai, Nigel Field, Justin Harbottle, Zahra Jamal, Sheena McCormack, Adrian Palfreeman, Mags Portman, Killian Quinn, Melinda Tenant-Flowers, Ed Wilkins, Ingrid Young

Guideline updates and date of next review

The guidelines are currently undergoing full review.


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