P177 Cross-sectional analysis of invasive pneumococcal disease in a London HIV-positive cohort
J Thornhill, E Wallis, S Cho, P Khan, A Sivaramakrishnan, A Amin and C Orkin
Barts Health NHS Trust, London, UK

P178 The emergence of new viral strains following treatment failure in an HIV-positive cohort infected with acute HCV
T Abdelrahman¹, J Hughes¹, J Main², J McLauchlan¹ and E Thomson^1
1MRC Centre for Virus Research, University of Glasgow, Glasgow, UK and ²Imperial College NHS Trust, London, UK

P179 Frequency and efficacy of EngerixB booster and Fendrix in HIV-positive patients with inadequate anti-HB s-antibody response
E Pool¹, G Morris², C Lacey³ and F Martin^3
1Hull and East Yorkshire Hospitals Trusts, Hull, UK, ²York Teaching Hospital NHS Foundation Trust, York, UK and ³University of York, York, UK

P180 Diagnosis of Pneumocystis jirovecii pneumonia by detection of DNA in blood and oropharyngeal wash, compared with sputum
C van Halsema¹, L Johnson¹, J Baxter¹, S Douthwaite¹, Y Clowes¹, M Guiver² and A Ustianowski^1
1North Manchester General Hospital, Manchester, UK and ²Health Protection Agency, Manchester, UK

P181 Injecting drug use is associated with treatment failure in HIV-positive men infected with acute hepatitis C
D Halperin, S Hindocha, J Main and E Thomson
Imperial College London, London, UK

P182 Trends in the use of liver biopsy in HIV-infected patients
R Lever, A Rodger, T Fernandez and S Bhagani
Royal Free Hospital, London, UK

P183 Does the dual-testing strategy under-diagnose latent TB infection in HIV-infected individuals? A 1-year experience in a TB high-incidence area in the UK
E Pease¹, A Ainley², M Curtiss¹, T Wambaa¹, J Ashby¹, S Dawson¹ and S Menzies^2
1Berkshire Healthcare NHS Foundation Trust, Slough, Berkshire and ²Heatherwood and Wexham Park Hospital Trust, Slough, Berkshire

P184 Liver Fibrosis stage found with liver biopsy or transient elastography in HIV-hepatitis C-coinfected patients
B Roca, V Torres, E Resino and MA Mendoza
General Hospital, University Jaume I, Castellon, Spain

P185 Clinical experience of boceprevir for the treatment of chronic hepatitis C in HIV co-infection
A Ahmed, S Pepper, E Page, M Anderson and M Nelson
Chelsea and Westminster Hospital NHS Foundation Trust, London, UK

P186 Hepatic safety profile of antiretrovirals in individuals infected with HIV and chronic hepatitis C
M Cevik¹, K Oh², S Scott¹, J Tan¹, M Bower¹ and M Nelson^1
1Chelsea and Westminster Hospital, London, UK and ²Imperial College Hospital, London, UK

P187 Hepatitis E IgG seroprevalence amongst HIV-infected patients at a London teaching hospital
M Toby¹, C Tong¹, R Serafino-Wani² and R Kulasegaram^1
1Guy's and St Thomas' NHS Foundation Trust, London, UK and ²Royal Free London NHS Foundation Trust, London, UK

P188 Reviewing BHIVA guidelines on screening for latent TB infection in HIV-positive patients in a high TB and HIV prevalence area in the UK
S Dakshina, L Foster, S Limb and R O'Connell
Barts Health NHS Trust, London, UK

P189 The use of antiepileptics for seizure treatment and prophylaxis in patients diagnosed with cerebral toxoplasmosis: What should be started, when should they be started and how long should they be continued?
O Liddle, P Saigal and F Post
King's College Hospital, London, UK

P190 Raltegravir (RAL) switch improves hepatitis C transaminitis in HIV-1 and hepatitis C (HCV)-co-infected individuals
M Cevik¹, L Dickinson², GS Singh¹, M Bower¹ and M Nelson^1
1Chelsea and Westminster Hospital, London, UK and ²Liverpool University, Liverpool, UK

P191 Experience of hepatitis C and HIV co-infection in a large inner city clinic
A Vas¹, J Broome¹, M Prince² and V Lee^1
1Manchester Centre for Sexual Health, Manchester, UK and ²Manchester Royal In?rmary, Manchester, UK

P192 Hepatitis C/HIV co-infection in the era of new hepatitis C treatment
N Hettiarachchi, Z-YV Ng and K Manavi
Queen Elizabeth Hospital, Birmingham, UK

P193 Audit of testing for cytomegalovirus on admission to a tertiary HIV facility
V Fletcher, A Hartley and G Baily
Royal London Hospital, Barts Health NHS Trust, London, UK

P194 Extensively drug-resistant tuberculosis (XDR-TB) in HIV: an experience shared
T Morris, N Venkatraman and D Bell
University Hospitals of Leicester NHS Trust, East Midlands (South), UK

P195 An HIV and TB co-infection clinic: patient characteristics, experience and outcomes
H Gill, R Chakraborty, M Dedicoat and S Barrett
Birmingham Heartlands Hospital, Birmingham, UK

P196 A case report of Progressive Outer Retinal Necrosis (PORN) in the context of very late diagnosis of HIV
J Thomas, J Evans-Jones and Colm O'Mahony
Countess of Chester Hospital, Chester, UK