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US HIV physicians routinely offering early ART but only a third have prescribed PrEP
by Michael Carter, 2015-10-06 10:20
Most doctors at the frontline of the HIV epidemic in the United States recommend early antiretroviral therapy (ART) and many also believe they have a role in providing pre-exposure prophylaxis (PrEP) to the uninfected partners of their patients living with HIV, according to research published in the online edition of Clinical Infectious Diseases.

Recent infection and ART treatment interruptions are key periods for HIV transmission
by Michael Carter, 2015-10-05 09:00
A large proportion of HIV transmissions occur during recent infection or antiretroviral treatment interruptions, Swiss investigators report in Clinical Infectious Diseases. Overall, 44% of transmissions were associated with recent infection and 14% could be attributed to treatment interruptions. The authors believe these findings represent a major challenge for treatment as prevention (TasP) strategies. “Our findings imply

New HCV NS5A inhibitor EDP-239 looks good in early studies, more evidence supports early hepatitis C treatment
by Liz Highleyman, 2015-10-05 08:00
A new hepatitis C virus (HCV) NS5A inhibitor being developed by Enanta – EDP-239 – was well-tolerated and demonstrated promising antiviral activity against genotype 1 HCV in a single-dose monotherapy study presented at the 55th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) last week in San Diego, USA. Other researchers reported that HCV co-infection and progressive liver disease

PrEP preferences in gay men are predicted by the frequency and predictability of the sex they have
by Gus Cairns, 2015-10-02 09:30
A recently-published survey from the US and Canada reveals that on the whole HIV-negative gay men would rather take pre-exposure prophylaxis (PrEP) intermittently and only before they anticipate sex, in what has been called “event-driven” or “on-demand” PrEP. The study was conducted in 2011 after the iPrEx study results came out and around the time

WHO guidelines recommend universal antiretroviral treatment, PrEP for those at substantial risk
by Liz Highleyman, 2015-09-30 17:40
The World Health Organization released updated guidelines today calling for antiretroviral therapy for everyone diagnosed with HIV regardless of CD4 T-cell count and pre-exposure prophylaxis (PrEP) for people at substantial risk of HIV infection. WHO estimates that if these recommendations are widely adopted worldwide, they could avert 21 million deaths and prevent 28 million new

The enduring power of stigma – understanding why HIV-positive gay men don’t disclose their status
by Roger Pebody, 2015-09-30 10:10
The accounts of a group of gay men living with HIV in Dublin, most of whom rarely if never disclose their HIV status to casual sexual partners, starkly reveal the extent of HIV stigma within the gay community, according to a qualitative study published online ahead of print in Qualitative Health Research. While interviewees feared