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Age difference in HIV infection matters – but it’s not always the younger person who is at risk
by Gus Cairns, 2018-03-19 07:30
A European study of men who have sex with men (MSM) presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2018) shows that age makes a considerable difference to whether a person is more likely to be infected with, or to transmit, HIV.Though it confirmed that younger gay men are more likely

New South Wales puts 9000 people on PrEP, achieves a one-third decline in new HIV infections
by Gus Cairns, 2018-03-15 07:40
The state of New South Wales in Australia has seen a fall of one-third in diagnoses of recent HIV infection since it started its PrEP implementation project, EPIC-NSW (Expanded PrEP Implementation in the Community), the CROI 2018 conference heard last week.Andrew Grulich of the Kirby Institute of the University of

Failure of second-line ART is common in resource-limited countries, but modern third-line regimens work well
by Liz Highleyman, 2018-03-14 11:30
More than half of people in low- and middle-income countries may not maintain viral suppression on second-line antiretroviral therapy (ART), according to a study presented at the 25th Conference on Retroviruses and Opportunistic Infections (CROI 2018) last week in Boston. This international trial showed that regimens containing boosted darunavir (Prezista) or

Lesotho making strong progress towards 90-90-90 targets
by Carole Leach-Lemens, 2018-03-14 07:50
Lesotho, in spite of a high HIV prevalence of over 25%, is making substantial progress toward meeting the UNAIDS 90-90-90 targets, with a reported 77% of adults who tested positive knowing their HIV status, Dr Thin of the Lesotho Ministry of Health told participants last week at the 25th Conference

Very early treatment in children limits the HIV reservoir
by Keith Alcorn, 2018-03-13 18:20
Very early HIV treatment in infants is feasible and safe and leads to a small reservoir of infected cells, two studies from Botswana and Thailand show. The findings offer hope that infants diagnosed and treated soon after birth will have a better chance of controlling HIV if future research leads

Isoniazid preventive therapy: do the risks outweigh the benefits in pregnant women with HIV?
by Carole Leach-Lemens, 2018-03-13 17:40
Isoniazid preventive therapy (IPT) during and after pregnancy in women living with HIV on antiretroviral therapy (ART) in tuberculosis (TB) endemic areas in Africa, Asia and Haiti resulted in serious adverse events quite possibly attributable to isoniazid (INH) with no significant reduction in TB cases, participants heard last week at

Treatment with extended-release naltrexone increases chances that HIV-positive prisoners will maintain viral suppression after release
by Michael Carter, 2018-03-13 08:00
Treatment with extended-release naltrexone is associated with improved viral suppression among HIV-positive prisoners, according to two US studies presented at the recent Conference on Retroviruses and Opportunistic Infections. Investigators followed patients for six months following their release into the community. Treatment with extended-release naltrexone was associated with a three-fold increase